Involvement of the Thalamic Parafascicular Nucleus in Mesial Temporal Lobe Epilepsy

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منابع مشابه

Neurobiology of Disease Involvement of the Thalamic Parafascicular Nucleus in Mesial Temporal Lobe Epilepsy

Mélanie Langlois,1 Pierre-Olivier Polack,3 Hélène Bernard,1 Olivier David,2 Stéphane Charpier,3 Antoine Depaulis,1 and Colin Deransart1 1Equipe 9, Dynamique des Réseaux Synchrones Epileptiques, and 2Equipe 5, Neuroimagerie Fonctionnelle et Métabolique, Grenoble Institut des Neurosciences, Institut National de la Santé et de la Recherche Médicale U 836-Université Joseph Fourier-Commisariat à l’E...

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Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy.

Mesial temporal lobe epilepsy (MTLE) is characterized by focal seizures, associated with hippocampal sclerosis, and often resistance to antiepileptic drugs. The parafascicular nucleus (PF) of the thalamus is involved in the generation of physiological oscillatory rhythms. It receives excitatory inputs from the cortex and inhibitory inputs from the basal ganglia, a system implicated in the contr...

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Impaired mesial synchronization in temporal lobe epilepsy.

OBJECTIVE Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. METHODS Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients' records of foramen ovale electrodes a...

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P11: The Role of Aquaporin-4Receotors in Mesial Temporal Epilepsy

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P 90: The Role of miR-146a in Inflammatory Process of Mesial Temporal Lobe Epilepsy (MTLE): Implication for Therapy

Epilepsy is the third most common chronic brain disorder which is characterized by an enduring predisposition to generate seizures. Mesial Temporal Lobe Epilepsy (MTLE) is the most common type of refractory epilepsy. Increasing evidence indicates that neuroinflammation plays a critical role in the pathogenesis of MTLE. Hundreds of micro-RNAs have been found to be abnormally expressed in epilept...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2010

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.1109-10.2010